課程資訊
課程名稱
 數量遺傳學
Quantitative Genetics 
開課學期
 111-1 
授課對象
 生物資源暨農學院  作物科學組  
授課教師
 黃永芬 
課號
 Agron5007 
課程識別碼
 621 U4920 
班次
  
學分
 3.0 
全/半年
 半年 
必/選修
 選修 
上課時間
 星期二3,4(10:20~12:10)星期五2(9:10~10:00) 
上課地點
 農藝304農藝304 
備註
 總人數上限：30人 
  
課程簡介影片
 
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課程概述

Quantitative traits – be they morphological, physiological, or developmental – show considerable variation within or among populations of a given organism. Most economically important traits in crops are quantitative. Indeed, quantitative genetics provides a theoretical basis for plant breeding. Modern quantitative genetics integrates knowledge from population genetics, statistical theories, mathematical modeling, genetics, and genomics, which is what we will go through in this 3-credit course. 

課程目標
 At the end of the course, the students are expected to have gained an understanding of fundamental concepts of population and quantitative genetics, explored how quantitative genetics principles can help a plant breeder in a breeding program, and appreciated the theory and experimental approaches which form the basis of breeding strategies. We aim to help students progress towards the acquisition of a critical self-learning ability, the ability that every plant breeder and society player needs. 
課程要求
 本課程所需的基礎知識除遺傳學及作物育種學外，尚需生物統計的基本知識（包括生物統計與試驗設計），部份課程需要用到迴歸分析與複因子試驗設計的初步概念。
必要先修課程包括：遺傳學、統計學、試驗設計；
建議先修或同時修習課程：農藝學統計法，高等統計學；
建議接續課程：分子育種學、育種試驗資料分析、育種學研究法、高等作物育種學、基因體統計方法導論 
預期每週課後學習時數
 ~ 3小時 
Office Hours
 另約時間 備註： Office hour is normally by appointment. Meanwhile, do come by the instructor’s office at your convenience to see whether she is available. 
指定閱讀
  
參考書目
 Bernardo R (2020) Breeding for quantitative traits in plants, 3rd edn. Stemma Press, Woodbury, MN, USA
Falconer DS and Mackay TFC (1996) Introduction to quantitative genetics, 4th edn. Pearson Education Limited, Essex, England, UK
Lynch M, Walsh B (1996) Genetics and analysis of quantitative traits. Sinauer Associates, Inc., Sunderland, MA, USA
Walsh B, Lynch M (2018) Evolution and selection of quantitative traits. Oxford University Press, New York, NY, USA 
評量方式
(僅供參考)
  
No.
項目
百分比
說明
1. 
 Homework or test 
50% 
 Homework and test at the first half of the semester. 
2. 
 Attendance and participation 
25% 
 Attendance in each lecture is required, as well as an active participation to the course. 
3. 
 Term report and Oral presentation 
25% 
 Term report and oral presentation for QTL mapping project. 
 
課程進度
週次
日期
單元主題
第1週
 09/06, 09/09  Syllabus; Introduction; Hardy-Weinberg equilibrium
09/09: 中秋節補休 
第2週
 09/13, 09/16  Hardy-Weinberg equilibrium (cont.); linkage; marker; small populations 
第3週
 09/20, 09/23  Inbreeding and relatedness
#Homework or Test 1# 
第4週
 09/27, 09/30  Phenotypic and genotypic values 
第5週
 10/04, 10/07  Breeding values
 
第6週
 10/11, 10/14  Mating designs and estimating genetic variances I
#Homework or Test 2# 
第7週
 10/18, 10/21  Mating designs and estimating genetic variances II 
第8週
 10/25, 10/28  Heritability I
 
第9週
 11/01, 11/04  Heritability II 
第10週
 11/08, 11/11  Linkage and recombination
#Homework or Test 3# 
第11週
 11/15, 11/18  11/15: 校慶停課
Construction of a linkage map 
第12週
 11/22, 11/25  QTL mapping 
第13週
 11/29, 12/02  QTL mapping
12/02: 全校運動會停課 
第14週
 12/06, 12/09  QTL mapping 
第15週
 12/13, 12/16  ## Written report + Oral presentation (linkage map + QTL mapping) ##
Reinventing quantitative genetics for plant breeding 
第16週
 12/20, 12/23  ## Debate: Reinventing quantitative genetics for plant breeding ##
End semester feedback